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Custom Library Adaptors Via Enzymatic DNA Synthesis Improve Precision of Real-Time Nanopore Sequencing
Australian Institute of Bioengineering and Nanotechnology, University of Queensland, AUSTRALIA
Tim Mercer leads a research team in genomics and bioinformatics at the AIBN, University of Queensland (mercerlab.org), and co-leads the BASE Facility, Australia’s foremost nucleic-acid biomanufacture facility that drives academic and commercial research into mRNA therapies and synthetic biology (www.basefacility.org.au). Tim Mercer and his team have undertaken basic research in genomics, noncoding RNAs and splicing that have been translated into biotechnologies widely adopted for research and clinical applications. Notable examples include the development of targeted RNA sequencing for the diagnosis of fusion-genes and the use of synthetic NGS controls for improving the accuracy of clinical genomics (www.sequinstandards.com).